Acknowledgements

The author is grateful to the following individuals for their contributions to this work: Dr. Dianne Camp (William Beaumont Research Institute) for her careful review and editorial suggestions; Drs. Robert Abel and Cathie Spino (Pfizer Global Research and Development - Michigan Laboratories: Ann Arbor Campus) for their assistance with the clinical trial examples; Ms Alice Birnbaum (Project Director, Axio Research) for her invaluable feedback on the multiple comparison macros; and Dr. Thomas Vidmar (Senior Director and Site Head, Midwest Nonclinical Statistics) for his support during this endeavor.