List of Abbreviations

AFLP
amplified fragment length polymorphism
ASCII
American Standard Code for Information Interchange
BAC
bacterial artificial chromosome
BAM
binary alignment/map
BIC
Bayesian information criterion
BLAST
basic local alignment search tool
BWA
Burrows–Wheeler algorithm
BWT
Burrows–Wheeler transformation
cDNA
complementary DNA
CINEMA
color interactive editor for multiple alignments
cRNA
complementary RNA
dbGaP
database of genotypes and phenotypes
dbVar
database of variation
DDBJ
DNA data bank of Japan
DEG
differentially expressed genes
DNA
deoxyribonucleic acid
DP
dynamic programming
EMBL
European Molecular Biology Laboratory
EST
expressed sequence tag
ExPASy
expert protein analysis system
F81 model
Felsenstein (1981) model
FASTA
fast all
FDQN
fully quantified domain name
FPKM
fragment per kilobase of exon per million mappable reads
GATK
genome analysis toolkit
gi or GI
gene identity
GO
gene ontology
GOR
Garnier, Osguthorpe, and Robson
GSS
genome survey sequence
GTF
gene transfer format
GTR
generalized time‐reversible
GUI
graphical user interface
GWAS
genome‐wide association studies
HKY85 model
Hasegawa, Kishino and Yano (1985) model
IBL
internal branch length
InDels
insertion and deletions
INSDC
International Nucleotide Sequence Database Collaboration
IUPAC
International Union of Pure and Applied Chemistry
JALVIEW
Java alignment viewer
JC69 model
Jukes and Cantor (1969) model
K80 model
Kimura (1980) model
MACAW
multiple alignment construction and analysis workbench
MAFFT
multiple alignment using fast Fourier transform
ME
minimum evolution
MEGA
molecular evolution and genetic analysis
MISA
microsatellite identification tool
ML
maximum likelihood
MP
maximum parsimony
MSA
multiple sequence alignment
MSRE
methylation sensitive restriction enzymes
MUSCLE
multiple sequence comparison by log‐expectation
mYa
million years ago
NBRF
National Biomedical Research Foundation
NCBI
National Center for Biotechnology Information
NGS
next‐generation sequencing
NJ
neighbor joining
NWA
Needleman–Wunsch algorithm
ORF
open reading frame
OTU
operational taxonomic unit
PDB
protein data bank
pI/MW
isoelectric point to molecular weight ratio
PIR
protein information resource
PSD
protein sequence database
PWMs
position weight matrices
RCSB
Research Collaboratory for Structural Bioinformatics
RE
restriction enzyme
RF
reading frame
RFLP
restriction fragment length polymorphism
RPKM
read per kilobase of exon per million mappable reads
rRNA
ribosomal RNA
SAM
sequence alignment/map
SCOP
structural classification of protein
SIB
Swiss Institute of Bioinformatics
SNPs
single nucleotide polymorphisms
SPR
subtree pruning regrafting
SSR
simple sequence repeats
STS
sequence‐tagged site
SWA
Smith–Waterman algorithm
T92 model
Tamura (1992) model
TBR
tree bisection reconnection
T‐Coffee
tree‐based consistency objective function for alignment evaluation
TFBS
transcription factor binding sites
TFs
transcription factors
TIS
translation initiation sites
TN93 model
Tamura and Nei (1993) model
T‐P
transversion‐parsimony
TPA
third‐party annotation
TPM
transcripts per million
TRANSFAC
transcription regulatory factors
tRNA
transfer RNA
TTS
triplex‐forming oligonucleotide target sequences
uGDT
unnormalized global distance test
UniProt
universal protein resource
UPGMA
unweighted pair group method with arithmetic mean
URL
uniform resource locator
VCF
variant call format
VNTR
variable number tandem repeat
WGS
whole genome shotgun
wwPDB
worldwide protein data bank
YAC
yeast artificial chromosome
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