INDEX

Page references given in bold indicate illustrations.

abbreviators, discourse against, 151

Ackerman, James, 136

aerial views, 71, 71, 72, 73

aerodynamics: and water flow, 33, 38, 58, 265, 267, 277–78

and bird flight, 186–87, 200–201, 252–53, 259–79, 269

compared to modern science, 265, 266, 267, 272, 278–79

and compressibility of air, 33, 252–54, 256, 266, 267, 278

and lift-to-drag ratio, 261–65

and mathematical reasoning, 261, 262, 263

and mechanical flight, 186, 251–54, 254, 255, 256, 256–60, 257, 260, 268, 272, 273, 274–76, 278–79

and pressure distribution, 262, 267, 278

and wind tunnel principle, 177, 261, 265, 278

air: as life-sustaining medium, 282, 298

mixed with blood, 284, 285, 286–87, 297, 298–99

Alberti, Leon Battista, 135, 218

Albert of Saxony, 89, 180

Albertus Magnus, 87, 110–11

algebra, 164, 169, 174, 175, 207

Alhazen (Ibn al-Haitham), 207

anatomy, human: and systemic thinking, 124, 125, 133–34, 284

and blood vessels, 25, 26, 29, 133, 145, 145, 212, 284, 285–88, 304, 305, 306–8

and bodily movement, 131, 133, 153–54, 211–14, 216, 225, 229, 233–34, 237, 240, 241

and bones, 130, 132, 133, 145, 212, 213, 228–31, 229, 230, 232, 233

and comparative anatomy, 133–34, 247–49, 250–51, 269, 272–73

compared to Alberti’s work, 218

compared to Vesalius’s work, 147–50

and critique of reductionism, 151

and dissections, 133, 144, 145, 217, 218, 219, 225–27, 234, 243, 245, 247, 248, 295, 304, 306, 314, 316

drawings related to, 128, 130, 131, 132, 133, 136, 137, 138, 143, 145, 145, 146, 147, 210, 212, 216–17, 220, 221, 224–25, 228–35, 229, 230, 232, 236, 237–41, 238, 242, 243, 243, 244, 245, 247–48, 248, 267, 305, 306, 306, 312

and female anatomy, 143, 143–44

and foot, 233, 240

geometry applied to, 131, 135, 137, 139, 141n, 142, 160, 234, 237

and hand, 132, 133, 231–33, 232

and harmonious relation, 136, 142–44, 150, 151

and heart, 134, 285–86, 287, 289–94, 292, 293, 295, 300, 312, plate 10

and integration of art and science, 217–19

and joints, 154, 213, 214, 228–29, 233–34

and Marcantonio della Torre’s work, 134

and mathematical reasoning, 131, 135, 139, 142, 235, 237

and mechanics, 131, 133, 153–58, 213, 234

medical texts used in, 144–45, 219, 221, 224

and muscles, 133, 145, 146, 154, 210, 212, 213, 214, 220, 233–35, 236, 237–40

and nervous system, 129, 131, 133, 135, 145, 211–12, 231, 240–41, 242, 243, 245, 291, 298

and optic nerve, 129, 131

painting related to, 218

and plans for De figura umana, 133, 225

and proportion, 128, 135–42, 137

and skull, 129, 130, 131, 135

and spine, 214, 216, 230, 230–31, 243, 243

and tendons, 133, 154, 212, 213, 233–35, 237–40

text and figure relation in, 221, 224, 239

and Vitruvian man, 128, 139–42, plate 5

Anderson, John, 272, 278

animal studies, 133–34, 136, 137, 138, 144, 243, 247–49, 250–51, 295, 315, 316. See also birds

antiquity, natural science in, 7–8

and anatomy, 144

and botany, 107–8, 110

and formation of the Earth, 86–87

and proportion, 135, 139–40, 141. See also Aristotelianism; Platonism

Arab natural philosophers, 87, 88, 144–45, 207

Arasse, Daniel, 62, 73, 320

Archimedes, 162–64, 166–69, 189, 191

architecture, 24, 135, 136, 140, 324

Aristotelianism, 5, 209

contrasted with Platonism, 139

and Earth as living body, 26, 66

and four-element theory, 40, 66

and geological change, 89, 91

and gravity, 40, 41, 174, 179, 192, 199

and human physiology, 283, 285

and motion, 173, 178–79, 181, 192

and vital force, 67n, 153

Aristotle: on animals, 108, 144

on bird flight, 252

on form, 8, 113

on geological change, 86, 88

on human heart, 283, 285

on plants, 108

Arno river, 23, 71, 71, 73, 94, 95

art, Renaissance, 62, 97–98

artworks, Leonardo’s. See drawings; paintings

Avicenna (Ibn Sina), 87, 144–45, 219, 283, 284

Bacon, Francis, 5, 154, 323

ballistics, 196–98, 209

beauty, quality of, 136, 137, 150

Bernoulli’s theorem, 35, 184, 262

Bertalanffy, Ludwig von, 311

Bertolini-Meli, Domenico, 173, 176

Bible, 19, 82, 88

biology: and systemic thinking, 281, 282

and Aristotelianism, 67n

and Earth as a living body, 65–68, 157

and evolutionary theory, 249–50

and fossils, 2–3, 80–85, 86

and water as life-giving element, 17–18, 20, 21, 22, 63, 281, 282. See also anatomy, human; animal studies; botany; physiology, human

biomimicry, 260

birds, 134, 154, 186–87, 200–201, 251, 252–53, 259–79, plate 1

flying machines modeled on, 156, 186, 251–54, 254, 255, 256, 256–60, 257, 260, 324

blood: and Earth as living body, 25–26, 29, 66, 67

and plants’ sap, 27, 67, 124, 284

and water, 18, 25–26, 27, 29, 63, 67, 118, 284, 285

flow of, 18, 134, 284, 285–88, 294–304, 306–8, 311, 312

mixed with air, 284, 285, 286–87, 297, 298–99

blood vessels, 25, 26, 29, 133, 145, 145, 212, 284, 285–88, 304, 305, 306–8

body, human. See anatomy, human; physiology, human

bones, 66, 67, 130, 132, 133, 145, 212, 213, 228–31, 229, 230, 232, 233

Borgia, Cesare, 73

botany, 97–98

and systemic thinking, 31, 117–18, 124–25

compared to modern science, 112, 113, 116, 118, 119–20, 124–25

and experiments, 119, 120

history of, 107–8, 110–12

and lost manuscript, 31, 112–13

and plant morphology, 113–18, 115, 117

and plant physiology, 113–14, 118–25, 282, 284

and religious symbolism, 98, 102, 104

represented in Leonardo’s drawings, 62, 96, 97, 99, 99–102, 101, 105–7, 106, 107, 108, 109, plate 6

represented in Leonardo’s paintings, 80, 98, 100, 102, 104–5, 106, plate 2, plate 8

and seeds, 124–25

and spiral movement, 62, 98–102, 114

and Trattato della pittura, 112, 114, 115, 120, 121, 123

and vital sap, 31, 67, 113–14, 116–18, 120–23, 284

Bottazzi, Filippo, 125

Botticelli, Sandro, 98

brachial plexus, 243, 244, 245

Bramante, Donato, 33

branching patterns: in human anatomy, 118, 124

in plants, 114–18, 124

in waterways, 118, 124

Brunelleschi, Filippo, 160

Buridan, Jean, 88–89, 180

calculus, 42, 174

canals, 23–24, 43, 71, 73, 159, 196

Cardano, Fazio, 160, 161

Castelli, Benedetto, 46

Chiana Valley, 72, 73

chiaroscuro, 77

Christ, Leonardo’s representation of, 19, 20, 77, 104, plate 2, plates 78

Clagett, Marshall, 165

Clark, Kenneth, 2, 160, 321

Codex Arundel: and botany, 105

and evolution, 250

and human physiology, 285

and mechanics, 164, 165, 176, 177, 189, 191, 192, 207

and water, 17, 24

Codex Atlanticus: and aerodynamics, 33, 253, 266

and botany, 122

and element of air, 282

and embryology, 313, 313

and fluid dynamics, 33, 38, 39, 55, 56

and flying machines, 258, 273, 274

and geology, 70, 75, 91

and mechanics, 163, 164, 171, 175, 176, 177, 189, 190, 201, 202–3

and water, 17, 21, 23

Codex Leicester: and fluid dynamics, 40, 51, 51–52, 52

and fossils, 81, 82, 83

and geology, 92, 94, 95, 133

and hydraulic engineering, 32

and mechanics, 168, 168, 170–71, 186, 206

and model of Earth, 90, 90

and water, 17, 28, 41, 69, 74

Codex Sul Volo, 154, 259, 260, 266, 267, 268–77, 272, 273, plate 1

Codex Trivulzianus: and aerodynamics, 253

and mechanics, 176, 180

Codices Forster, 176

Codices Madrid: and mechanics, 152, 158, 161, 166, 166–67, 167, 170, 171, 172, 172, 175, 183, 183, 185, 186, 195, 195–97, 197, 200

and water, 17

cognitive science, 131, 156, 318

communicating vessels, 171–72

comparative anatomy, 133–34, 247–49, 269, 272–73

complex systems, theory of, 10, 12, 22, 25, 311

conservation of energy, 181–84, 200, 208

Corte Vecchia, Leonardo’s workshop at, 4, 252, 254

Coulomb, Charles, 186

Daedalus, myth of, 251, 251

Darwin, Charles, 75, 120, 249

Deluge, biblical story of the, 82, 83

deluge drawings, 58–62, 59, 60, 61, 278

Democritus, 8, 33, 113

Descartes, René, 8, 113, 154, 155–56, 157, 181, 198

digestion, 214, 283, 288, 298, 308–11

disorder. See order and disorder, in nature

dissections, 133, 134, 144, 145, 217, 218, 219, 225–27, 234, 243, 245, 247, 248, 295, 304, 306, 314, 316

dragons, 214, 215, 216

drawings, Leonardo’s: anatomical knowledge represented in, 128, 130, 131, 132, 133, 136, 137, 138, 143, 145, 145, 146, 147, 210, 212, 216–17, 220, 221, 224–25, 228–35, 229, 230, 232, 236, 237–41, 238, 242, 243, 243, 244, 245, 247–48, 248, 267, 269, 305, 306, 306, 312, plates 35, plates 910

botanical knowledge represented in, 62, 96, 97, 99, 99–102, 101, 105–7, 106, 107, 108, 109, plate 6

and collaboration with other artists, 99, 99–100

deluge, 58–62, 59, 60, 61, 278

exploded view in, 224, 231, 237, 238

and five Platonic solids, 135

flying machines represented in, 254, 254, 255, 256, 256–58, 257, 260, 260, 273

geological knowledge represented in, 64, 74, 75, 75, 76, 77, 90, 90, 94, 95

and grotesques, 135

mechanical knowledge represented in, 152, 158, 160, 162, 163, 166, 166, 167, 168, 168, 172, 172, 183, 185, 187, 191, 191, 193, 195, 195, 197, 197–98, 198, 203, 203, 205, 207, 208

physiological knowledge represented in, 285, 289–92, 292, 296, 300, 300, 304, 305, 306, 312, 313, 314, 315

self-portrait, 322

and studies for paintings, 99, 99–102, 101, 103, 105, 106

and water studies, 15, 16, 28, 29, 38, 39, 43, 43, 49–51, 50, 53, 54, 55–58, 56, 57, 59, 60, 61, 101, 197–98, 198, 267, 267, 278

in youth, 102

Dürer, Albrecht, 136

dynamic conception of nature, 8–9, 21, 32–33, 68, 99, 137, 139, 249, 281. See also aerodynamics; fluid dynamics

Earth: axial precession of, 88n

drawing of, 90

formation of, 86–87, 88

internal processes of, 87–94

as living body, 25–26, 65–68, 73, 95, 129, 133, 157, 249, 285

shape of, 88, 89, 90

structure of, 88, 90–91. See also geology

ecology, 9, 281, 282

and ecological design, 324–25

eddy, water. See vortex, water

Einstein, Albert, 199

Ellenberger, François, 84, 94

Emboden, William, 80, 97, 98, 104, 105, 106, 107, 108, 110, 111, 112–13, 114, 116, 119–20, 122, 123, 124

embryology, 124–25, 135, 224, 312–14, 313, 315, 316–18, plate 9

empirical method, 5–7, 9

energy, concept of, 181–82. See also conservation of energy

engineering: and geological observations, 65, 69, 73, 94

and hydraulic projects, 23–24, 31–32, 43, 71, 73, 159, 196, 324

Leonardo’s employment in, 31, 32, 43, 158, 196, 252

mechanical, 155, 158–62, 187, 200, 252, 258

and military projects, 73, 158–59, 196. See also machines; mechanics

entropy, 188

equilibrium: hydrostatic, 166–72, 167

static, 162–66

Eratosthenes, 86

Euclid, 141n, 161, 162

Euler, Leonard, 35

evolutionary theory, 75, 249–50

experiments, 5–6, 89

botanical, 119, 120

fluid, 28, 33, 35, 37–39, 40, 41, 183–84

mechanical, 158, 162, 164, 166, 166, 168, 170, 171, 174, 185–86, 187, 193, 194, 202, 203, 204, 206, 208, 252, 254

optical, 201, 252

exploded view, in Leonardo’s drawings, 224, 231, 237, 238

explosive phenomena, 202–3

Faraday, Michael, 199

Fasciculus medicinae (medical text), 219, 224

Fasso, Constantino, 170, 173

Fermat, Pierre de, 201

fetus, human. See embryology

Feynman, Richard, 34

fish, 251, 267, 267

flight, science of. See aerodynamics floods: and geological studies, 69, 74

and hydraulic projects, 23

represented in Leonardo’s drawings, 278

witnessed by Leonardo, 23. See also Deluge, biblical story of the

Florence: “anatomy of the artists” practiced in, 217–18

as center of Platonism, 139

Giotto’s campanile in, 251, 251

Leonardo’s activity in, 139, 154, 251, 259, 268, 271

fluid dynamics, 33–35

and comparison between air and water, 33, 38, 58, 265, 267, 277–78

and Aristotelianism, 40–41

and Bernoulli’s theorem, 35, 184, 262

and bluff body flows, 50, 51

and complexity theory, 22

and conservation of energy, 183, 183–84

and conservation of mass, 42–43

and continuity principle, 43, 45, 46

and distinction between flow and wave motion, 36–37

effect of gravity on, 39, 40, 153

and Euler’s work, 35

and experiments, 28, 33, 35, 37–39, 40, 41, 183–84

and flow visualization, 37, 38, 39, 39, 50, 51, 55, 58

and geology, 69, 73, 94

and granular materials, 33

and Helmholtz’s work, 48

and mathematical reasoning, 31, 34–35, 39, 41, 42–43, 45, 48, 53, 58, 60

and Navier-Stokes equations, 34, 35

and Newton’s third law, 201

and perpetual motion, 187–88

and rates of flow, 39–40, 44–46

and Reynolds number, 34, 53

and Richardson cascade, 50

and viscosity (friction), 34, 35, 39, 41–42, 50, 153, 181, 186

and vortex motion, 22, 46–49, 47, 50, 51, 52, 52, 55, 60, 61–62, 101, 124, 281. See also hydrostatics; turbulence; water

flying machines, 156, 186, 251–54, 254, 255, 256, 256–60, 257, 260, 268, 272, 273, 274–76, 278–79, 324

foot, 233, 240

form. See matter vs. form

fossils, 2–3, 80–85

four-element theory, 36, 40, 66, 88, 173

friction: and aerodynamics, 262

and fluid dynamics, 34, 39, 41–42, 153, 181

and geological erosion, 69

and human physiology, 285, 295, 296–97, 299, 307

and mechanics, 162, 181, 184–87, 195

Gaia theory, 25, 68

Galen, 144, 145, 219, 283, 284, 288–89, 294–99, 303, 309, 313

Galileo Galilei, 5, 8, 41, 113, 174, 175–76, 179, 181, 193, 194, 195, 196, 198, 268

Galluzzi, Paolo, 155, 159

genius, Leonardo as, 1–4, 9

geology: and systemic thinking, 66, 133

and Aristotelianism, 66, 89, 91

and catastrophic events, 92–93

compared to modern science, 65, 68, 70, 75, 84, 89, 90, 93–94

and Earth as living body, 65–68, 73, 95, 129, 133

and Earth’s internal processes, 89–94, 95

and Earth’s shape and structure, 89–91, 90

as engineer, 65, 69, 73, 94

and erosion, 21, 68, 69–70, 74, 77, 78–80, 86, 90, 91, 92, 94, 188

and fossils, 2–3, 80–85, 86

and Gaia theory, 68

and maps, 70, 71, 72, 73, 94

and mountains, 69, 85–86, 89, 91, 92, 94

represented in Leonardo’s artworks, 20, 64, 65, 68, 74, 75, 75, 76, 77, 90, 90, 94, 95, 102, 320, plate 8

and sedimentation, 68, 70, 74, 75, 78, 80, 81, 82, 94

tectonic theory anticipated in, 89–93, 153, 180

and time, 65, 74–75, 77, 84, 94–95, 188, 189

and water as geological agent, 21, 66, 67, 68, 69–70, 74, 82, 83, 89, 90, 91, 92, 93, 94, 95, 153, 188

and weathering, 78–80, 188. See also Earth

geometry: and anatomy, 131, 135, 137, 139, 141n, 142, 160, 234, 237

Euclidean, 141n, 161

and mechanics, 160, 161, 162, 163, 169, 173, 174, 175, 182, 191–92

and model of Earth, 89–91, 90

of motion, 42–43, 182

and optics, 131, 160, 201

and water flow, 42–43. See also proportion

Giacomelli, Raffaele, 252

Goethe, Johann Wolfgang von, 2, 8, 113, 249

golden section, 136

Gould, Stephen Jay, 70, 84, 91

grace, quality of, 211

gravity: Aristotelian concept of, 40–41, 174, 179, 192, 199

center of, 90–91, 92, 191–92, 214

and falling bodies, 192–96

and fluid flow, 39, 40, 153

modern theories of, 198–99

Greece, ancient, natural science in. See antiquity, natural science in; Aristotelianism; Platonism

grotesques, Leonardo’s drawings of, 135

Hamilton, William Rowan, 201

hand, 132, 133, 231–33, 232

harmony, 136, 142–44, 150, 151

Harvey, William, 294, 295, 297, 298

Havel, Václav, 11

heart: action of, 214, 283–89, 293–94, 295, 299–303, 311–12

Aristotle’s conception of, 283

Avicenna’s conception of, 283

Galen’s conception of, 283, 288–89, 294

glass model of aorta of, 301

structure of, 134, 285–86, 287, 289–94, 292, 293, 295, 300, plate 10

and Valsalva’s work, 300, 302

heat, of human body, 283, 284, 285, 288, 295, 296–99, 303, 309, 312

Helen of Troy, 189

Helmholtz, Hermann von, 48

Helmont, Jan Baptista van, 119

Heraclitus, 33

herbals, Renaissance, 111

Heron of Alexandria, 44–45

Highmore, Nathaniel, 313n

Hildegard of Bingen, 110

Hippocrates, 219

holistic memory, 4, 11

holistic perspective, 7

in Leonardo’s work, 142–45, 147, 151

Hooke, Robert, 178

hormones, plant, 113, 118, 120, 122, 123, 124

horses, 136, 137, 138, 247–48, 248

humanism, Italian, 139

humors (vital fluids), 18, 26, 27, 113, 116, 157, 281, 284. See also vital spirits

Hutton, James, 84, 88

Huygens, Christiaan, 177, 178, 207

hydraulic engineering, 23–24, 31–32, 43, 71, 73, 159, 196, 324

hydrodynamics. See fluid dynamics

hydrostatics, 166–72, 167

Imola, 72, 73

impetus, theory of, 173, 179–81, 193, 196, 267, 270, 271

inclined-plane experiments, 41, 186, 193, 193–94, 208, 314

inertia, principle of, 179–81, 197, 208, 267

Ingenhouz, Jan, 120

Islam, natural philosophy cultivated in, 87, 88, 144–45, 207

joints: avian, 263, 269

human, 154, 213, 214, 228–29, 233–34

Jordanus de Nemore, 164

Kant, Immanuel, 8, 113

Keele, Kenneth, 155, 228, 233, 292, 303, 312, 313, 316, 321

Kemp, Martin, 68, 77, 84–85, 279, 320

kinematics. See motion

Laurenza, Domenico, 139, 141, 142, 144, 145, 147–51, 217, 221, 224, 228, 247, 256

Leibniz, Gottfried Wilhelm, 182

Lenoble, Robert, 179

Leo X, Pope, 318

Leonardo da Vinci, life of: certified as master painter, 99, 218

in childhood, 23, 65, 102

employed at Sforza court, 31, 32, 43, 158, 159, 218, 252

and employment as engineer, 31, 32, 43, 158, 196, 252

and flooding in Tuscany, 23

as genius, 1–4, 9

as member of painters’ guild, 218

and Pope Leo X’s ban on dissections, 318

and relations with Cesare Borgia, 73

and relations with Donato Bramante, 33

and relations with Brunelleschi, 160

and relations with Cardano, 160, 161

and renown as artist, 77, 196

and renown as engineer, 196

as resident of Amboise, 318

as resident of Florence, 139, 154, 218, 251

as resident of Milan, 31, 77, 81, 131, 139, 154, 158, 189, 218–19, 251–52, 289, 312

as resident of Rome, 59, 252, 289, 312, 318

as student of Verrocchio, 19, 28, 99, 160, 217, plate 2

and visits to seashore, 36–37

and visit to Pavia, 160–61, 162

levers, 154, 161–66, 189, 190, 191, 200, 213

life. See biology linear relationships, 41, 168, 171, 175–78, 192–94, 268

liver, 304, 305, 306–9, 317

living system, 9–10, 22, 25, 30, 68, 124, 143, 157, 282

Lovelock, James, 68

Lucretius, 87

lungs, 66, 214, 283, 288, 295, 296, 297

Lyell, Charles, 75, 84

Macagno, Enzo, 32, 169

machines: development of, 158–62, 200

friction in, 185–86

human body compared to, 154–58

perpetual motion, 187–88. See also flying machines

macrocosm/microcosm relation: and biological processes, 18, 281, 282

difference of underlying forces in, 25, 153

and Earth as living body, 25, 66, 129

and proportion, 136

and qualitative form, 8

and water cycle, 25

Manuscript A: and fluid dynamics, 33, 45, 46–47, 47, 55

and geology, 66

and macrocosm/microcosm relation, 66

and mechanics, 161, 176, 179, 187, 187, 200, 204, 205, 207, 208, 208

and water, 17, 24

Manuscript B: and botany, 123

and flying machines, 254, 255, 256, 256, 257, 258

Manuscript C: and mechanics, 161, 197, 198, 203, 203

and water, 281

Manuscript E: and bird flight, 266–67, 277–78

and mechanics, 165, 165, 176, 178, 181

and water, 17

Manuscript F: and aerodynamics, 271

and fluid dynamics, 44, 55

and geology, 92, 133

and mechanics, 200

and water, 32, 43

Manuscript G: and bird flight, 276

and botany, 105, 115, 119, 120, 282

and fluid dynamics, 267, 267

and heart structure, 290, 291

and mechanics, 180, 201

and water, 17, 21, 30

Manuscript H, fluid dynamics in, 42, 50, 51

Manuscript I: and botany, 116

and fluid dynamics, 42, 55

and mechanics, 173, 178

and water, 17

Manuscript K: and bird flight, 259, 266, 268

and water, 17

Manuscript L: and bird flight, 259

and water, 17

Manuscript M: and botany, 116, 117

and mechanics, 193

maps, 35, 70, 71, 72, 73, 94

Materia medica, 110, 111

mathematics: and aerodynamics, 261, 262, 263

and anatomy, 131, 135, 139, 142, 235, 237

and fluid dynamics, 31, 34–35, 39, 41, 42–43, 45, 48, 53, 58, 60

and mechanics, 154, 160, 162, 163–64, 169, 173, 174, 175, 177, 182, 190, 193, 196, 198, 201, 207. See also algebra; calculus; geometry

matter vs. form, in Western science, 7–9, 113

Maxwell, James Clerk, 199

mechanics: Archimedean, 162–64, 166–69, 189, 191

and center of gravity, 191–92, 209

and communicating vessels, 171–72

and energy conservation, 181–84, 200, 208

and energy loss, 184–89, 195, 202, 208

and energy transfer, 202, 204, 206

and experiments, 158, 162, 164, 166, 166, 168, 170, 171, 174, 185–86, 187, 193, 194, 202, 203, 204, 206, 208, 252, 254

and Fermat’s work, 201, 208

and force, 173, 174, 176, 178–79, 183, 190, 198–201

and friction, 162, 181, 184–87, 195

and Galileo’s work, 174, 175–76, 179

geometry applied to, 160, 161, 162, 163, 169, 173, 174, 175, 182, 191–92

and Hamilton’s work, 201

and human anatomy, 131, 133, 153–58, 213, 234

and Huygens’s work, 177, 207

and hydrostatics, 166–72, 167

and impact phenomena (percussion), 183, 200, 202–4, 205, 206–8

and Leibniz’s work, 182

and levers, 154, 161–66, 189, 190, 191, 200, 213

and linear relationships, 168, 171, 175–78, 192–94, 268

and mathematical reasoning, 154, 160, 162, 163–64, 169, 173, 174, 175, 177, 182, 190, 193, 196, 198, 201, 207

and Newton’s work, 174, 179, 182, 200, 209, 252

and Pascal’s principle, 169–72

and principle of least action, 201–2, 208

and pulleys, 154, 161, 165, 166, 168, 190, 200, 213, 258, 272

and pyramidal relationships, 175, 176

and reflection, 207–8, 208

and statics, 162–66, 171

variables of, 174–76

and weights, 162–66, 189–92

and work, 200. See also motion

mechanistic philosophy, Leonardo’s organic approach contrasted with, 154–56, 157, 158

medical texts, 144–45, 219, 221, 224

Medici family, 99, 139

Melzi, Francesco, 112

Michelangelo, 1, 62

microcosm. See macrocosm/microcosm relation

Middle Ages, natural science in: and botany, 110–11

and geology, 81–82, 88

and medicine, 144

and proportion, 135

Milan: “anatomy of the doctors” practiced in, 217, 218–19

Aristotelianism taught in, 139

Leonardo’s activity in, 31, 77, 81, 131, 139, 154, 158, 189, 218–19, 251–52, 289, 312

military projects, 73, 94, 158–59, 196

Minot, Charles, 316

momentum, 181

Mondino de Luzzi, 145, 219, 284

morphology, plant, 113–18, 115, 117

motion, 173, 176–78

Aristotelian concept of, 173, 178–79, 181, 192

and ballistic trajectories, 196–98, 209

circular, 177–78

and Descartes’s work, 181

of falling bodies, 192–96

and Galileo’s work, 175–76, 179, 181, 193, 194, 195, 196, 198

of human body, 131, 133, 211–14, 216, 225, 229, 233–34, 237, 240, 241

and impetus, 173, 179–81, 193, 196, 267, 270, 271

and inertia, 179–81, 197, 208, 267

and momentum, 181

and Newton’s work, 35, 179, 198, 200, 209, 252

and pendulum swing, xxvi, 194–95, 195, 196, 208

perpetual, 187–88

relativity of, 177, 208, 253, 265, 266, 278

spiral, 62–63, 98–102, 114, 124, 177–78

and Torricelli’s work, 198

and waves, 36–37. See also aerodynamics; dynamic

conception of nature

fluid dynamics

gravity

Mozart, W. A., 2

murals in Sforza Castle, 106–7

muscles, 132, 133, 145, 146, 154, 210, 212, 212, 213, 214, 220, 233–35, 236, 237–40

Nathan, Johannes, 137, 144

Navier-Stokes equations, 34

Needham, Joseph, 317

neptunism, geological theory of, 87, 88

nervous system, 129, 131, 133, 135, 145, 211–12, 231, 240–41, 242, 243, 245, 291, 298

Newton, Isaac, 1, 2, 3, 8, 35, 39, 113, 154, 174, 188, 198–99, 200, 209, 252

nonlinear dynamics, 34

Nuland, Sherwin, 234, 301–2, 316

O’Malley, C. D., 228, 235, 240, 302, 306

open systems, theory of, 12, 311

optics, 131, 160, 201, 207–8

order and disorder, in nature, 188, 250

organic conception of nature: and anatomy, 136, 145, 150

and botany, 97, 99, 100, 113, 118, 124

contrasted with mechanistic conception, 154–56, 157, 158

and fluid dynamics, 17–18, 21, 22

Orr, David, 10–11

Ovid, 189

Pacioli, Luca, 135

paintings, Leonardo’s: anatomical knowledge represented in, 218, 251

botanical knowledge represented in, 80, 98, 100, 105, 106, plate 8

botanical symbolism in, 98, 102, 104

and collaboration with other artists, 80, 105

geological knowledge represented in, 20, 74, 77–80, 79, 94, 95, 102, 320, plate 8

and portrait of Prince Ludovico’s mistress, 31

religious signification in, 18–19, 20, 77, 98, 102, 104

states of mind registered in, 36, 216

by title: Annunciation, 251

Baptism of Christ, 19, plate 2

Last Supper, 4, 36, 189, 216, 252

Leda and the Swan, 62, 100–102, 101, 103, 106, 318, 319, 320, 321

Madonna and Child with Saint Anne, 19, 20, 74, 95, 211, 216, 318, plate 7

Mona Lisa, 19, 20, 95, 216, 318, 320–21, plate 11

Saint Jerome, 218

Saint John the Baptist, 62

Virgin of the Rocks, 19, 20, 31, 77–80, 79, 94, 98, 100, 102, 104–5, 106, plate 8. See also murals in Sforza Castle

Pascal, Blaise, 169–72

Pavia, Leonardo’s activity in, 160–61, 162

Pedretti, Carlo, 112

pendulum motion, xxvi, 194–95, 195, 196, 208

perception, 131

percussion (impact phenomena), 183, 200, 202–4, 205, 206–8

perpetual motion, 187–88

perspective, 131, 161

pharmacology, 110, 111

photosynthesis, 119–20

physics. See gravity; mechanics; motion

physiology, human: and aging, 306–8

and Earth as living body, 66–68, 157, 281, 285

and analogy with plant physiology, 284

and Aristotelianism, 283

and blood-air mixture, 284, 285, 286–87, 297, 298–99

and blood flow, 18, 134, 284, 285–88, 294–304, 306–8, 311, 312

and body heat, 18, 283, 284, 285, 288, 295, 296–99, 303, 309, 312

and digestion, 214, 283, 288, 298, 308–11

drawings related to, 285, 289–92, 292, 296, 300, 300, 304, 305, 312, 313, 314, 315

and embryology, 124–25, 135, 224, 312–14, 313, 314, 315, 316–18, plate 9

and friction, 285, 295, 296–97, 299, 307

and Galen’s work, 283, 284, 288–89, 294–99, 303, 309, 313

and Harvey’s work, 294, 295, 297, 298

and heart action, 214, 283–89, 293–94, 295, 299–303, 311–12

and heart structure, 285–86, 287, 289–94, 292, 293, 295, plate 10

and liver, 304, 305, 306–9, 317

and lung action, 214, 283, 288, 295, 296, 297

and macrocosm/microcosm relation, 66, 281, 282

and respiration, 214, 283, 288, 296

and vital spirits, 232, 283, 284, 285, 288–89, 295, 298–99, 302, 303, 309, 310, 312. See also anatomy, human

Piomelli, Ugo, 49

Pizzorusso, Ann, 77, 78, 80

plants: as decorative motifs in art, 97–98

hormones in, 113, 118, 120, 122, 123, 124

medical properties of, 110, 111

morphology of, 113–18

photosynthesis in, 119–20

physiology of, 113–14, 118–25, 282, 284

religious symbolism of, 98, 102, 104. See also botany

Platonism, 25, 135, 139

Pliny the Elder, 86, 108, 110

plutonism, geological theory of, 87

Poincaré, Henri, 42

Pollaiolo, Antonio del, 217

Polyclitus, 135

Predis, Ambrogio de, 80, 105

Prigogine, Ilya, 311

printing press, 224

proportion, 135–42

Ptolemy, 86

pulleys, 154, 161, 165, 166, 168, 190, 200, 213, 258, 272

pyramidal relationships, 175, 176. See also linear relationships

Pythagoras, 7, 8, 113

qualities, science of, 8, 10, 139

Raphael, 1

reductionism, critique of, 151

reflection, 207–8, 208

relativity, general, Einstein’s theory of, 199

relativity of motion, 177, 208, 253, 265, 266, 278

religion, as theme in Leonardo’s artworks, 18–19, 20, 77, 98, 102, 104

Reti, Ladislao, 161

Reynolds number, 34, 53

Richardson cascade, 50

Richter, Jean Paul, 105

Roberts, Jane, 107

rock cycle, 92

rock formations. See geology

Rome, ancient, natural science in. See antiquity, natural science in

Rome, in Renaissance period, Leonardo’s activity in, 59, 252, 289, 312, 318

Santerno river, 73

sap, in plants, 27, 31, 67, 113–14, 116–18, 120–23, 284

Saunders, J. B., 228, 235, 240, 302, 306

scientific method, 5–7, 84

sculpture, 5, 84, 135–36, 160, 217, 251, 251

self-organizing systems, 68, 318

self-portrait, Leonardo’s, 322

Sforza, Ludovico, 31, 252

Sforza Castle, Milan, Leonardo’s murals in, 106–7

Sforza court, Milan, Leonardo’s activity at, 31, 32, 43, 158, 159, 218, 252

Shakespeare, William, 2

skeleton. See bones

skull, human, 129, 130, 131, 135

solids, five Platonic, 135

soul, Leonardo’s doctrine of: and Aristotelianism, 153, 283

and brain as “seat of the soul,” 131, 241

compared to Cartesian doctrine, 156, 157

and Earth as living body, 67

and fetal development, 317–18

and integrative function, 156, 157

spine, human, 214, 216, 230, 230–31, 243, 243

spiral movement, 62–63, 98–102, 114, 124, 177–78

spiritual force and action, 199, 211–12, 240, 298

Star of Bethlehem, botanical drawing of, 62, 96, 101, plate 6

statics, 162–66, 171

Steno, Nicolas, 70n

Stoics, natural philosophy of, 86

Strabo, 86

stratigraphy, 70n

sun, life-sustaining power of, 282, 284

systematic approach, 6, 136, 161, 197, 218, 252, 281

systematic experiments and expositions, 40, 41, 81, 129, 158, 190, 204, 231, 233, 254

systematic studies, 218

systemic thinking, ix–x, 4, 5, 6, 7–9, 11, 13, 84, 117, 151, 185, 196, 208, 249, 323

systemic conception of life, 25

systemic understanding of life, xii, 10

systems science, 8

systems theory, 22, 25

systems view of life, x

tectonic theory, 89–93, 153, 180

tendons, 66, 132, 133, 154, 212, 213, 233–35, 237–40

Theophrastus, 108, 111

thermodynamics, laws of, 184–85, 188, 208, 250

time: and biological evolution, 249, 250

and geological processes, 65, 74–75, 77, 84, 94–95, 188, 189, 249

and irreversible processes, 188–89, 208

Titian, 147

topological thinking, 42, 48, 73, 142

Torre, Marcantonio della, 134

Torricelli, Evangelista, 198

Trasimene, lake, 73

Trattato della pittura, 93, 112, 114, 115, 115, 120, 121, 123, 142

turbulence: and air flow, 58–62, 59, 60, 261, 263, 267, 281

and blood flow, 18, 285, 295, 296, 297, 299, 300, 300, 301, 303

as coherent structure, 22, 55

drawings related to, 49–53, 50, 51, 52, 53, 54, 56, 57, 59, 60, 61

experiments related to, 37–38

modern theories of, 22, 33–35

and water flow, 22, 33–35, 37–38, 49–62, 50, 51, 52, 53, 54, 56, 57, 58, 59, 60, 61, 281

Tuscany, Leonardo’s activity in, 65, 295. See also Florence

uniformitarianism, geological theory of, 84

vacuum, 28, 194

Valsalva, Antonio, 300, 302

velocity, angular vs. linear, 177–78

Verrocchio, Andrea del, 19, 28, 99, 160, 217, plate 2

Vesalius, Andreas, 147–50, 148, 149, 150

viscosity, 34, 35, 39, 41–42, 50, 153, 181, 186

vision, 131

visualization, flow, 37, 38, 39, 39, 50, 51, 55, 58

vital spirits, 232, 283, 284, 285, 288–89, 295, 298–99, 302, 303, 309, 310, 312

Vitruvian man, 128, 139–42, plate 5

Vitruvius, 135, 139–40, 141

vivisection, 133n, 294–95, 309

vortex, water, 22, 46–49, 47, 50, 51, 52, 52, 55, 60, 61–62, 101, 124, 281

vulcanism, geological theory of, 87

water: and air flow, 33, 38, 265, 267, 277–78

and blood, 18, 25–26, 27, 29, 30–31, 63, 67, 118, 284, 285

and analogy with plants’ sap, 27, 31, 117–18, 124

distillation of, 18, 28, 29, 285

and Earth as a living body, 25–26, 29, 67, 285

evaporation of, 24, 31

geological significance of, 21, 66, 67, 68, 69–70, 74, 82, 83, 89, 90, 91, 92, 93, 94, 95, 153, 188

as humor, 18, 26, 27, 157, 281, 284

and hydrostatics, 166–72, 167

incompressibility of, 33, 39, 42

jets of, 49, 50, 50, 55–57, 197–98, 198, 209

as medium for biological processes, 17–18, 20, 21, 22, 63, 281, 282

religious significance of, 18–19, 20

represented in Leonardo’s drawings, 15, 16, 28, 29, 38, 39, 43, 43, 49–51, 50, 53, 54, 55–58, 56, 57, 59, 60, 61, 101, 197–98, 198, 267, 267, 278

represented in Leonardo’s paintings, 18–20

siphoning of, 28, 29

and water cycle, 24–31, 67, 284–85

and waterfalls, 55–58, 56, 57. See also fluid dynamics

wave motion, 36–37

Windsor Collection: and anatomical drawings, 130, 132, 133, 137, 138, 143, 143, 145, 146, 216n, 220, 221, 228, 229, 230, 232, 233, 236, 237, 238, 239, 241, 242, 243, 244, 247, 248, 269, 269, plates 34, 9–10

and anatomical notes, 151

and botanical drawings, 106, 106, 107, 107, plate 6

and botanical notes, 112, 124

and deluge drawings, 59, 59–62, 60, 61

and embryological drawings, 312, 314, 315, 316, plate 9

and geological drawings, 75, 75, 76

and maps, 71, 72

and physiological drawings, 285, 289–92, 292, 300, 300, 304, 305, 312

and representations of bodily movement, 214, 214, 215

and water studies, 17, 29, 43, 49–51, 50, 52, 53, 53, 54, 55–58, 56, 57

wind tunnel, 177, 261, 265, 278

Wren, Christopher, 199

Zöllner, Frank, 137

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