Becoming a cloud native company is undeniably a journey, and one that is not only focused on technology. As demonstrated by the Netflix case study, this journey can take a very long time to do correctly and will often be full of tough decisions, including those relating to technology and business trade-offs. In addition, this journey is never-ending. The cloud is still in its infancy and the innovations being delivered by major cloud vendors are accelerating, not slowing down. This chapter will identify the drivers that are often used to make a cloud adoption decision. It will examine the frameworks that are commonly used as organizations start down the cloud adoption path and will explain what components and approaches are taken with a cloud migration. Finally, it will describe how to build a comprehensive cloud operating model that takes into consideration the challenges of risk, security, and QA in the cloud.