Contents
1.1 About Receiver Operating Characteristic Curves
Chapter 2 Single Binary Predictor
2.4 Sensitivity and Specificity
2.5 Computations Using PROC FREQ
Chapter 3 Single Continuous Predictor
3.1 Dichotomizing a Continuous Predictor
3.3 Empirical ROC Curve and the Conditional Distributions of the Marker
3.5 Selecting an Optimal Threshold
3.7 Transformations to Binormality
3.8 Direct Estimation of the Binormal ROC Curve
3.9 Bootstrap Confidence Intervals for the Area under the Curve
Chapter 4 Comparison and Covariate Adjustment of ROC Curves
4.2 An Example from Prostate Cancer Prognosis
4.3 Paired versus Unpaired Comparisons
4.4 Comparing the Areas under the Empirical ROC Curves
4.5 Comparing the Binormal ROC Curves
4.6 Discrepancy between Binormal and Empirical ROC Curves
4.7 Bootstrap Confidence Intervals for the Difference in the Area under the Empirical ROC Curve
4.8 Covariate Adjustment for ROC Curves
4.9 Regression Model for the Binormal ROC Curve
5.3 Empirical ROC Curve for Ordinal Predictors
5.4 Area under the Empirical ROC Curve
5.6 Comparing ROC Curves for Ordinal Markers
Chapter 6 Lehmann Family of ROC Curves
6.2 Lehmann Family of Distributions
6.3 Magnetic Resonance Example
6.5 Using Estimating Equations to Handle Clustered Data
6.6 Comparing Markers Using the Lehmann Family of ROC Curves
6.7 Advantages and Disadvantages of the Lehmann Family of ROC Curves
Chapter 7 ROC Curves with Censored Data
7.3 ROC Curves with Censored Data
7.4 Concordance Probability with Censored Data
7.5 Concordance Probability and the Cox Model
Chapter 8 Using the ROC Curve to Evaluate Multivariable Prediction Models
8.3 Resubstitution Estimate of the ROC Curve
8.4 Split-Sample Estimates of the ROC Curve
8.5 Cross-Validation Estimates of the ROC Curve
8.6 Bootstrap-Validated Estimates of the ROC Curve
Chapter 9 ROC Curves in SAS Enterprise Miner
9.3 ROC Curves from SAS Enterprise Miner for a Single Model
9.4 ROC Curves from SAS Enterprise Miner for Competing Models
9.5 ROC Curves Using PROC GPLOT with Exported Data from SAS Enterprise Miner
Appendix An Introduction to PROC NLMIXED
A.1 Fitting a Simple Linear Model: PROC GLM vs PROC NLMIXED